Study of the Prevalence of Food Allergens in Patients with Allergies Admitted to Mofid Children’s Hospital During 2010 to 2016

Fereshte Dehghan Banadaki, Mahboubeh Mansouri, Reza Shekarriz-Foumani

Abstract

Introduction: Allergic diseases include a wide range of symptoms such as asthma, rhinitis, urticaria, eczema, and gastrointestinal symptoms that are becoming increasingly prevalent in today’s world. Exposure to food allergens is one of the contributing factors for allergic diseases in humans. The identification of susceptibility to food allergens plays an important role in the prevention and treatment of allergic diseases.

Materials and Methods: After the clinical diagnosis of allergic diseases, patients were examined using the skin prick test.The method of collecting data was observational. All data were entered in SPSS software version 21 and analyzed using descriptive and inferential statistics.

Results: A total of 466 patients with a mean age of                          years were studied, of which 58.6% were boys and 41.4% were girls. A total of 44.2% patients had asthma, 21.7% had allergic rhinitis, 2.1% had allergic sinusitis, 1.7% had conjunctivitis, 1.1% had angioedema, 11.6% had urticaria, 19.7% had eczema, and 26.8% had gastrointestinal allergic symptoms. A total of 114 patients (24.5%) had food allergies, of which 43.9% were girls and 56.1% were boys. In terms of the age and gender of patients, no statistically significant difference was observed between different food allergens (P<.05). The most common allergens in patients under study were peanuts (7.9%), milk (7.3%), almond (6.6%), freshwater fish (6.6%), and walnuts (6.4%).

Conclusion: The findings revealed that allergen prevalence in each region is influenced by its climatic conditions, people’s food habits, their racial differences, and their lifestyles.

Keywords

Allergic Diseases, Food Allergens, Skin Prick Test, Children

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References

Kay AB, Bousquet J, Holt PG, Kaplan AP. Allergy and allergic diseases. 2nd ed. Hobokon: John Wiley & Sons; 2009.

Saadeh D, Salameh P, Baldi I, Raherison C. Diet and allergic diseases among population aged 0 to 18 years: myth or reality? Nutrients 2013; 5: 3399-423.

He S-h, Zhang H-y, Zeng X-n, Chen D, Yang P-c. Mast cells and basophils are essential for allergies: mechanisms of allergic inflammation and a proposed procedure for diagnosis. Acta Pharmacol Sin 2013; 34:1270-83.

Jahad Daneshgahi of Tehran University of Medical Sciences. Allergy subspecialty clinic 2018 [cited 2018 1/7/2018]. Available from: http://allergyclinic.ir/fa/index.php/1389-08-24-11-03-02/1389-08-24-14-06-39.html.

Hughes DA, Mills C .Food Allergy: a problem on increase. Biologist (London) 2001; 48: 201-204.

Kanny G, Moneret-Vautrin DA ,Flabbee J , Beaudouin E , Morisset M. Population Study of food allergy in France .J Allergy Clin Immunol 2001 ;108 :133-140.

R.A. Wood. The natural history of food allergy. Pediatrics 2003; 111:1631–1637.

Hosseini S, Shoormasti RS, Akramian R, Movahedi M, Gharagozlou M, Foroughi N, et al. Skin Prick Test Reactivity to Common Aero and Food Allergens among Children with Allergy. Iranian Journal of Medical Sciences 2014; 39(1): 29-35.

Morris MJ, Argyros Col GJ, Batuello SG, Bessman E, Blackburn P, Brenner BE, et al. Asthma. Available at: http://emedicine.medscape.com/ article/296301-overview Accessed February 2, 2012.

International Rhinitis Management Working Group. International consensus report on the diagnosis and management of rhinitis. Allergy1994; 49: 1-34.

Milgrom H, Leung DYM. Allergicrhinitis. In: Kliegman RM, Stanton BF, St. Geme J, Schor N, Behrman RE, eds. Nelson Textbook of Pediatrics. 19th ed. Philadelphia, Pa: Saunders Elsevier; 2011. pp 775-780.

Howarth PH, VonMutius E, Martinez FD. Allergic and non allergic rhinitis. Natural history, development and prevention of allergic disease in childhood. In: Middleton's Allergy: Principles and Practice E-Dition, Franklin Adkinson N Jr, Yunginger JW, Busse WW, Bochner BS, Estelle F, Simons R, et al. 5th ed. USA: Mosby; 2003. pp 131-1407.

Leung DY. Atopic dermatitis (Atopic eczema). In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF. Nelson Textbook of Pediatrics. 4th ed. Philadelphia: Saunders Company 2007; 970-5.

Leung DY, Eichenfield LF, Boguniewicz M. Atopic Dermatitis. In: Fitzpatrick TB, Wolff K, Goldsmith LA, Katz S, Gilchrest BA, Paller AS, et al. Fitzpatrick's dermatology in general medicine. 6th ed. Philadelpihai: Mc Grow Hill 2008; 146-8.

Soter NA, Kaplan AP. Urticaria and angioedema. In: Freedberg IM, Eisen AZ, Wolff K, Austen KF, Goldsmith LA, and Katz SI. Fitzpatrick's dermatology in general medicine. 6th ed. New York: McGraw-Hill. 2003; 1129-39.

Confino-Cohen R, Chodick G, Shalev V, Leshno M, Kimhi O, Goldberg A. Chronic urticaria and autoimmunity: associations found in a large population study. J Allergy Clin Immunol. 2012; 129 (5): 1307-13.

Zuberbier T, Asero R, Bindslev-Jensen C, Walter Canonica G, Church MK, Gimenez-Arnau A et al. EAACI/GA(2)LEN/EDF/WAO guideline: definition, classification and diagnosis of urticaria. Allergy 2009; 64: 1417–1426.

Katta R, Schlichte M. Diet and dermatitis: food triggers. J Clin Aesthet Dermatol 2014;7:30-36.

Moghtaderi M, Aleyasin S, Amin R, Kashef S. Skin test reactivity to fungal aeroallergens in asthmatic children in southern Iran. Iran J Pediatr 2010; 20(2): 242-245.

Kim HO, Cho SI, Kim JH, Chung BY, Cho HJ, Park CW, et al. Food hypersensitivity in patients with childhood atopic dermatitis in Korea. Ann Dermatol 2013; 25: 196-202.

Salehi T, Pourpak Z, Karkon S, Shoormasti RS, Sabzevari SK, Movahedi M, et al. The study of egg allergy in children with atopic dermatitis. World Allergy Organ J 2009; 2: 123-127.

Farrokhi S, Gheybi M, Movahed A, Iranpour D, Ostovar A, Vahdat K, et al. Evaluation of the frequency of food and aeroallergens in patients with eczema and urticaria in province of Bushehr: based on skin prick test reactivity. ISMJ 2011;17: 629-637.

Heinzerling L, Mari A, Bergmann K-C, Bresciani M, Burbach G, Darsow U, et al. The Skin Prick test-European standards. Clin Transl Allergy 2013; 3: 3.

Onsouri F, Ahmadi A, Mansouri M, Mousavi Khourshidi SM, Pazouki N, Salimian J. The prevalence of food allergens in patients with atopic dermatitis referred to allergy and asthma clinic in Tehran in 1393. Journal of Kurdistan University of Medical Sciences April 2016; 21: 40-46.

Keshvari S, Shirkani A, Tahmasebi R, Omrani AM, Farrokhi Sh. Association Between Allergic Diseases and Food Allergens Based on Skin Prick Test in Bushehr Province. Iran South Med J 2017; 20(1): 46-56.

Ahanchian H, Jafari SA, Jabbari Azad F, Kianifar HR, Karimi N,Khakshour A, Kiani MA. Evaluation of common allergens in children with atopic dermatitis by skin prick test. Journal of North Khorasan University of Medical Sciences Autumn 2013; 5(3): 551-555.

Farajzadeh S, Bazargan N, Shahesmaeili A, Gholami Shahrbabaki A, Fekri AR. Evaluation of the Frequency of Food Allergens by Skin Prick Test in Children with Atopic Dermatitis. Iranian Journal of Dermatology Summer 2010; 13 (2): 33-36.

Kim HO, Cho SI, Kim JH, Chung BY, Cho HJ, Park ChW, and Lee ChH. Food Hypersensitivity in Patients with Childhood Atopic Dermatitis in Korea. Ann Dermatol 2013; 25(2): 196–202.

Burks AW, Tang M, Sicherer S, Muraro A, Eigenmann PhA. ICON: Food allergy. Journal of Allergy and Clinical Immunology April 2012; 129 (4): 906–920

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