Case Report
Published February 19, 2019
Article Tools
Article Level Metrics
Share this article
facebook twitter linkedin


Ocular Squamous Cell Carcinoma
Ocular Surface Squamous Neoplasia
Eye Pain

How to Cite

Hundal, J., Ali, M., Ferguson, K., Saffra, N., & Babu, B. (2019). Pain: More than Meets the Eye, an Atypical Case of Ocular Squamous Cell Carcinoma. Internal Medicine and Medical Investigation Journal, 4(1).

Pain: More than Meets the Eye, an Atypical Case of Ocular Squamous Cell Carcinoma

Jasmin Hundal
Madiha Ali
Kyle Ferguson
Norman Saffra
Benson Babu
Cornell University, Lower Manhattan


  Eye pain is common and initially managed by primary care physicians. In the rare refractory case or atypical appearance, consultation with ophthalmology is needed. 

Case presentation

A 35-year-old Hispanic male patient with a history of pterygium presented with complaints of worsening left eye pain for months .Over the past two weeks, the patient had also noticed more redness and soreness that occurred all day.  He noticed darkening in the medial vision of his left eye, persistence of left eye pain and visual changes. An excisional biopsy of the lesion was performed.  The final biopsy reports revealed an ocular surface squamous cell carcinoma in situ arising from pterygium.


Topical application and injections of immunotherapy such as mitomycin C and 5-fluorouracil have been shown to be effective.  Recurrence is high and follow-up examination by ophthalmology is essential.
Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.