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Segmental Longitudinal Strain (SLS)
Global Longitudinal Strain (GLS)
Coronary Artery Disease (CAD)

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Radfar, M., Ashrafi, M., Sheikhvatan, M., Sadeghian, A., & Sadeghian, H. (2019). Determining the Changes in Value of Segmental Longitudinal Strain and Global Longitudinal Strain in Discriminating Left Anterior Descending Artery Involvement. Internal Medicine and Medical Investigation Journal, 4(3). https://doi.org/10.24200/imminv.v4i3.225

Determining the Changes in Value of Segmental Longitudinal Strain and Global Longitudinal Strain in Discriminating Left Anterior Descending Artery Involvement: SLS and GLS Changes in Discriminating LADA Involvement

Mehran Radfar
Department of Cardiology, Shariati Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
MohammadMoein Ashrafi
Young Researchers and Elites Club, Faculty of Medicine, Islamic Azad University, Yazd Branch, Yazd, Iran
Mehrdad Sheikhvatan
Pars Advanced and Minimally Invasive Medical Manners Research Center, Pars Hospital, Iran University of Medical Sciences, Tehran, Iran
Afsaneh Sadeghian
Bahar Hospital, Shahrood University of Medical Science, Shahrood, Iran
Hakimeh Sadeghian
Department of Cardiology, School of Medicine, Shariati Hospital Tehran University of Medical Sciences, Tehran, Iran

Introduction: The present study was conducted to determine the predictive role of the segmental longitudinal strain in predicting significant proximal left anterior descending stenosis in patients with coronary heart disease regarding specific cardiac segments.

Materials and Methods: This cross-sectional study was conducted on 90 consecutive patients who were candidates for coronary angiography and assessed using speckle-tracking echocardiography. All patients underwent echocardiography prior to coronary angiography and only patients with normal left ventricular ejection fraction were finally included. Besides, conventional echocardiography, all patients were subjected to speckle-tracking echocardiography determination, and the images were assessed in standard 3C, 2C, 4C views.

Results: 45 patients with significant proximal left anterior descending stenosis found from the coronary angiography report and 45 patients with had normal coronary arteries. Based on the surface area under the receiver operating characteristic curve analysis, the highest diagnostic ability to distinguish between left anterior descending involvement from normal coronary state was related to the segmental longitudinal strain of the septal basal segments (AUC = 0.962), anteroseptal apical (AUC = 0.942) and septal mid portion (AUC = 0.941) . For global longitudinal strain it was -20.45 (100% sensitivity, 95.5% specificity) regarding the global longitudinal strain diagnostic value in the prediction of proximal significant left anterior descending stenosis.

Conclusion: The measurement of segmental longitudinal strain in LAD segments and global longitudinal strain can predict proximal left anterior descending stenosis with high sensitivity and specificity.



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