Determining the Changes in Value of Segmental Longitudinal Strain and Global Longitudinal Strain in Discriminating Left Anterior Descending Artery Involvement: SLS and GLS Changes in Discriminating LADA Involvement
Introduction: The present study was conducted to determine the predictive role of the segmental longitudinal strain in predicting left anterior descending involvement in patients with suspected coronary heart disease regarding specific cardiac segments.
Materials/Methods: This cross-sectional study was conducted on 90 consecutive patients who were candidates for coronary angiography and assessed using speckle-tracking echocardiography. All patients underwent echocardiography prior to coronary angiography and only patients with normal left ventricular ejection fraction were finally included. Besides, conventional echocardiography, all patients were subjected to speckle-tracking echocardiography determination, and the images were assessed in standard 3C, 2C, 4C views.
Results: 45 patients with left anterior descending found from the coronary angiography report and 45 patients with suspected coronary artery disease, but had normal coronary arteries. Based on the surface area under the receiver operating characteristic curve analysis, the highest diagnostic ability to distinguish between left anterior descending involvement from normal coronary state was related to the segmental longitudinal strain of the septal basal segments (AUC = 0.962), Posterior apical (AUC = 0.948), anteroseptal apical (AUC = 0.942), septal mid portion (AUC = 0.941) and inferior mid-portion (AUC = 0.911). For global longitudinal strain it was -20.45 (100% sensitivity, 95.5% specificity) regarding the global longitudinal strain diagnostic value in the prediction of left anterior descending conflict.
Conclusion: The evaluation of segmental longitudinal strain in various segments and global longitudinal strain can predict left anterior descending involvement with high sensitivity and specificity.
This work is licensed under a Creative Commons Attribution 4.0 International License.