The Prevalence of Iron Deficiency Anemia among High School Students in Iran: A Systematic Review


Iron Deficiency Anemia
High School Students

How to Cite

Alipoor, R., Gholami, M. S., Heidari-Soureshjani, R., Rajabi, M. reza, Anari, M. J., Vaziri, M. S., Vajdi, S., & Shamshirian, A. (2017). The Prevalence of Iron Deficiency Anemia among High School Students in Iran: A Systematic Review. Internal Medicine and Medical Investigation Journal, 2(1), 1-6.


Introduction: Iron is one of the most important elements forming the body and an essential metal for many biological processes in mammals. According to studies, anemia can cause numerous side effects in the body. Because of the effectiveness of iron in myelinated nerves, this illness can cause hearing loss and vision problems as well, and in students, it can even cause academic failure and learning problems and intensify behavioral disorders. Therefore, to collect the statistics of the prevalence of the disorder in order to inform parents, the present study was conducted to assess the prevalence of iron deficiency anemia in high school students in Iran using meta-analysis method.

Method: This study was continued in review form using the key words anemia, iron deficiency anemia, and anemia prevalence with a review of the articles in Pubmed, Iranmedex databases and Scientific Information Database of SID in related topics with 89 articles. Time domain for searching articles and related books and was mainly from 1991 onwards.

Results: Studies on the prevalence of iron deficiency anemia in high school students show different results. Recent statistics based on published articles at home and abroad show the prevalence of iron deficiency anemia equal to 10.6%, (with a 95% confidence interval: 9.7 to 11.5) until 2014.

Conclusion: The disease can cause hearing and vision disorders in adolescents. Moreover, it can cause academic failure and learning problems and intensify behavioral disorders in students.  Given that children's health is an indicator of health planning of family for them, attention to the factors preventing iron deficiency anemia and its treatment is essential for students. Following this study, it is suggested that by correcting diet as the first step of prevention of catching this diseases, we take a step towards preventing it.


- Hallberg L, Sandstrom B, Ralph A, Arthur J. Iron, zinc and other trace elements. 10 ed. Garrow J, James W, Ralph A, editors. London: Churchill livingstone; 2000.

- Heeney MM, Finberg KE. Iron-Refractory Iron Deficiency Anemia (IRIDA). Hematology/oncology clinics of North America. 2014;28(4):637-52.

- Szymlek-Gay EA, Ferguson EL, Heath AL, Gray AR, Gibson RS. Food-based strategies improve iron status in toddlers: a randomized controlled trial12. The American journal of clinical nutrition. 2009;90(6):1541-51.

- Zohouri FV, Rugg-Gunn AJ. Sources of dietary iron in urban and provincial 4-year-old children in Iran. Asia Pacific journal of clinical nutrition. 2002;11(2):128-32.

- Chaleshgar M, Hosseini M, shojaiezadeh D, Pishva H. A Study of Knowledge , Attitude and Practice of Girl Students of Guidance Schools in Ghaemshahr on Iron Deficiency Anemia. Toloo-e-Behdasht. 2006;2(5):1-12.

- Kliegman R, Nelson WE. Nelson textbook of pediatrics. 19th ed. Philadelphia, PA: Elsevier/Saunders; 2011. lxvii, 2610 p. p.

- Algarin C, Peirano P, Garrido M, Pizarro F, Lozoff B. Iron deficiency anemia in infancy: long-lasting effects on auditory and visual system functioning. Pediatric research. 2003;53(2):217-23.

- Bonuck KA, Kahn R. Prolonged bottle use and its association with iron deficiency anemia and overweight: a preliminary study. Clinical pediatrics. 2002;41(8):603-7.

- Anderson JJ. The Status of Adolescent Nutrition. Nutrition Today. 1991;26(2):7-10.

- Bull NL. Dietary habits, food consumption, and nutrient intake during adolescence. The Journal of adolescent health : official publication of the Society for Adolescent Medicine. 1992;13(5):384-8.

- Duggan C, Watkins JB, Walker WA. Nutrition in pediatrics : basic science, clinical application. 4th ed. Hamilton: BC Decker; 2008. xvii, 923 p. p.

- Farthing MC. Current Eating Patterns of Adolescents in the United States. Nutrition Today. 1991;26(2):35-9.

- Lifschitz C. New actions for old nutrients. Acta Sci Pol Technol Aliment. 2012;11:183-92.

- Skinner JD, Salvetti NN, Ezell JM, Penfield MP, Costello CA. Appalachian adolescents' eating patterns and nutrient intakes. Journal of the American Dietetic Association. 1985;85(9):1093-9.

- Thomas JA, Call DL. Eating between meals--a nutrition problem among teenagers? Nutrition reviews. 1973;31(5):137-9.

- Abdollahi Z. Evaluation of anemia caused by iron in the 14- to 18-year high school in the region, 15 in the south of Tehran. Tehran: Tehran University of medical Sciences; 1992.

- Bigler-Doughten S, Jenkins R. Adolescent snacks: nutrient density and nutritional contribution to total intake. Journal of the American Dietetic Association (USA). 1987;35:24-9.

- Kersting M, Alexy U, Sichert-Hellert W. Vitamin intake of 1- to 18-year-old German children and adolescents in the light of various recommendations. International journal for vitamin and nutrition research Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung Journal international de vitaminologie et de nutrition. 2000;70(2):48-53.

- Loth KA, MacLehose RF, Fulkerson JA, Crow S, Neumark‐Sztainer D. Are food restriction and pressure‐to‐eat parenting practices associated with adolescent disordered eating behaviors? International Journal of Eating Disorders. 2014;47(3):310-4.

- Pooraram H, Aminpoor A, Kalantari N, Golestan B, Abtahi M. The IDA and compare factors in adolescent girls in urban and rural. Payesh Journal. 2003;4(2):267-75.

- Dizegi A, Gholami Yarizad E, Jamshibeigi E. The prevalence of iron deficiency anemia and their treatment among high school students of Ilam in 1375-76 . Ilam Sientific Journal. 2000; 8 (28) :23-28.

- Abolfathi AA , Kimiagar M , Vallaei N , Ghaffarpour M , Poorghassem B , M Ghaffarpour. Prevalence of Iron deficiency, anemia and Iron deficiency anemia in Jolfa high school students. Pajoohandeh Journal. 1377; 3 (12) :25-30.

- AR Vahidi , N Parsaeian. Prevalence of Iron deficiency anemia in Yazd high school students. Journal of Shahid Sadoughi University of Medical Sciences And Health Services. 1378; 7 (1) :31-5.

- Houshangnezhadeh A, Asgari M, Shams A, Valaie N, Fouladimoghadam A. The prevalence of Iron deficiency, anemia, and iron deficiency anemia in high school students, Varamin, 1998-99. Pajoohandeh Journal. 2014; 19 (5) :228-234.

- Fakhre- Movahedi A, Ahadi F. Prevalence of Iron Deficiency Anemia in High School Girls in Semnan City. JSSU. 2005; 12 (4) :51-55.

- T Khazaei , M Zardast , SAR Saadat Joo. Prevalence of Iron deficiency anemia in Birjand high school students. Journal of Birjand University of Medical Sciences 1382؛ 10(15):29-33.

- Mozaffari-Khosravi H, Noori Shadkam M, Naghiaee Y. Prevalence of Iron Deficiency and Iron Deficiency Anemia in High-School Girl Students of Yazd. JSSU. 2009; 17 (3) :135-141.

- Korourian A, Mirhoseyni M. The Prevalence of Iron Deficiency Anemia in High School Students of Baft in 2009. mljgoums. 2014; 7 (4) :90-95.

- Akramipour R, Rezaei M, Rahimi Z. Prevalence of iron deficiency anemia among adolescent schoolgirls from Kermanshah, Western Iran. Hematology. 2013 Jul 18.

- Achouri I, Aboussaleh Y, Sbaibi R, Ahami A, El Hioui M. Prevalence of Iron Deficiency Anaemia Among School Children in Kenitra, Northwest of Morocco. Pakistan Journal of Biological Sciences. 2015 Feb 15;18(4):191.

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