Determining Prognostic Value of Serum Levels of Lactate, Bicarbonate, Base Deficit and Glucose in Mortality Rate of Trauma Patients Admitted to Emergency Department

Roozbeh Rajai Ghafouri, Mahboob Pouraghaei, Amir Ghffarzad, Roya Shokri, Leila Azizkhani

Abstract

Introduction: Trauma is of the most important health problems in the world and major factor leading to mortality and morbidity, especially in the first four decades of life in injured people. So, we decided to examine in this study clinical symptoms and laboratory parameters in trauma patients and predictive value in determining prognosis and mortality of these patients.

Materials and Method: In this descriptive study, 150 cases of multi-trauma patients admitted to the emergency department of Tabriz Imam Reza hospital were enrolled in the study. Computerized block randomization method was applied to randomize the subjects The questionnaire containing basic information in the pre-hospital phase were recorded for selected patients. As well, injury severity score (ISS) and revised trauma score (RTS) were calculated. Then, blood samples were taken from patients for testing laboratory parameters, including serum lactate level, base deficit, blood glucose, serum bicarbonate levels, BUN and Cr. The data obtained were analyzed through descriptive statistics, frequency, percentage and mean difference test and chi-square test for qualitative variables examined using the software statistical SPSS v17. The P value<0.05 was considered statistically significant.

Results: mean age of patients was equal to 37.05±1.58 years. 130 patients (87.8%) were discharged after treatment and recovery and 18 patients (12.2%) died. predictive values of serum lactate cut of point was 27.65 pg/ml for serum lactate with sensitivity of 80% and specificity of 48% on admission.

Conclusion: It seems that the mentioned markers alone are unable to be potent prognostic factors as predictors of mortality

Keywords

Multiple Trauma, Mortality, Emergency Service

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