Author(s): Nedasadat Mansouritehrani
The most common complications following anesthesia intubation
include postoperative sore throat, post-extubation cough, and hoarse voice. Currently,
the use of preoperative Dexamethasone has been effective in controlling these complica-
tions. Therefore, the present study aimed to compare the preemptive effect of intracuff
and intravenous routes of Dexamethasone administration for postoperative sore throat
and cough.
Materials and Methods:
In the present clinical trial, 96 patients who under-
went general anesthesia intubation were randomly assigned to three groups. The first
group received 4 mg intracuff Dexamethasone, the second group received 4 mg intrave-
nous Dexamethasone, and the third group was administered a placebo. Cough frequen-
cy and severity of a sore throat after extubation were investigated in the three groups.
Results:
Any significant difference was not observed among the three groups regarding
hemodynamic variables (P>0.01); however, the incidence of cough was significantly
lower in all the three groups (P<0.01). Also, the average severity of a sore throat in
PAR and 1 h after surgery in the three groups was significantly lower (P<0.05). Moreo-
ver, no difference was detected in the groups regarding the severity of a sore throat
within 24 h post-surgery (P>0.01).
Conclusion:
The use of two methods of intravenous
and intracuff Dexamethasone administration before surgery reduced the incidence of
postoperative cough and the severity of sore throat in patients